The TCP transport layer protocol is designed for connections that traverse a single path between the sender and receiver. However, there are several environments in which multiple paths can be used by a connection simultaneously. In this paper we consider the problem of supporting striped connections that operate over multiple paths. We propose an end-to-end transport layer protocol called pTCP that allows connections to enjoy the aggregate bandwidths offered by the multiple paths, irrespective of the individual characteristics of the paths. We show that pTCP can have a varied range of applications through instantiations in three different environments: (a) bandwidth aggregation on multi-homed mobile hosts, (b) service differentiation using purely end-to-end mechanisms, and (c) end-systems based network striping. In each of the applications we demonstrate the applicability of pTCP and how its efficacy compares with existing approaches through simulation results.